Thus, in our model, we accessed the bronchoalveolar lavage levels of cytokines associated with different cellular profiles, IL-4 and IL-13 (Th2), INF-γ (Th1) and IL-17 (Th17) of XID and BALB/c mice before infection (day 0) and 7 and 9 days after infected with C. gattii. This evidence concerns the gene IL4 and infection.