Anti-tumor effects of IL-12 have been proved in models of renal cancer25 and in anti-melanoma combination therapies with cyclophosphamide26, endoglin-based DNA vaccine27, CAMEL peptide28, D-K6L9 peptide29, anti-vascular ABRaA-VEGF121 chimeric protein30 and tumor cell lysate31. Here, ENG is linked to neoplasm.