Out of these, 12 were known to be associated with ADs (CDH2, DLG4, DRD1, GRIK2, MAPT and NTRK2 associated with OCD, NTRK3 with OCD and panic disorder, ADORA2A with panic disorder and specific phobia, GAD1 with GAD and panic disorder, NPY with GAD, panic disorder and specific phobia, GAD2 with GAD, OCD and panic disorder, and DRD2 with GAD, OCD, SAD and specific phobia). The gene discussed is CDH2; the disease is generalized anxiety disorder.