While Lt-OATP1B3 (the translated product of Lt-SLCO1B3) was mostly found as a membrane-bound protein on the cell surface, Ct-OATP1B3 (the translated product of Ct-SLCO1B3) was mainly detected in the cytoplasm of colon cancer cells [15]. The gene discussed is SLCO1B3; the disease is malignant colon neoplasm.