While we were aiming to corroborate the previous reports of IGF-2 efficacy, as inter-laboratory reproducibility is a long-standing goal of ours, we did establish strong reproducibility with other rat studies [16, 71–73], EEG and sleep studies [72, 74–77, 82], and other genetic mutant mouse models of neurodevelopmental disorders [51, 56, 78]. This evidence concerns the gene IGF2 and neurodevelopmental disorder.