Moreover, we observed that T2DM subjects in the highest serum albumin quartiles exhibited higher levels of eGFR, ABI, and lower serum Cr, CysC and ACR compared with those in the lowest quartile, and serum albumin was negatively associated with serum Cr, CysC, and ACR, indicating that serum albumin levels may be associated with DN and PAD as diabetic micro- and macrovascular complications, respectively, which were consistent with the results of previous reports [17, 37–39]. The gene discussed is ALB; the disease is complication.