After adjusting for age, gender, BMI and diabetic duration, the associations among serum albumin and metabolic parameters (DBP, TC, TG, HDL-C, HbA1c), inflammation and oxidative stress parameters (NLR, UA and GGT), and diabetic nephropathy (DN) related parameters (serum Cr, CysC and ACR) remained statistically significant (P < 0.01 or P < 0.05; Table 2). The gene discussed is ACR; the disease is liver dysplastic nodule.