PVALB and schizophrenia: Because of the close relationship between these two systems, Steullet et al. [23] believed that the neuroimmune system, OxS, and glutamatergic system constitute a “central hub,” and that the disturbance of these “hub” systems may lead to the abnormality of parvalbumin interneurons and white matter in patients with schizophrenia through the dysfunction of macro-circuits and micro-circuits.