In this study, the percentage of plaque rupture was higher than plaque erosion and calcified nodule in patients with ASCVD, while the Apo B/A1 ratio in plaque rupture or erosion groups were both higher in ACS than that of CCS patients (rupture: 36.0 vs. 16.0% and erosion: 22.3 vs. 6.6%). The gene discussed is APOB; the disease is atherosclerosis.