ERBB2 and neoplasm: WGS analysis or fluorescence in situ hybridization (FISH) analysis in a Clinical Laboratory Improvement Amendments (CLIA)–certified cytogenetics laboratory did not detect ERBB2 gene amplification in the primary patient tumor, nor was it detected by WGS or FISH in BCX1, BCX1TamR1, or BCX1TamR2 PDX tumors (fig.