SPECC1 and infection: The formation of early infection viroplasms requires co‐expression of the Ser/Asp/Glu‐rich acidic protein NSP5 and a positively charged RNA chaperone NSP2 (Fabbretti et al, 1999; Eichwald et al, 2004; Silvestri et al, 2004; Papa et al, 2020a) that appear to dynamically change their post‐translational modifications, e.g. phosphorylation and hyperphosphorylation of NSP5 (Poncet et al, 1997; Sen et al, 2006; Campagna et al, 2007; Papa et al, 2020a), and potentially of NSP2 (Criglar et al, 2018) over the course of infection.