RNA binding protein 20 (RBM20) cardiomyopathy is a recently identified unique form of cardiomyopathy afflicting approximately 3% of patients with dilated cardiomyopathy (DCM) (Brauch et al., 2009; Guo et al., 2012; Linke & Bücker, 2012; Refaat et al., 2012). The gene discussed is RBM20; the disease is dilated cardiomyopathy.