Colon cancer cells infected with F. nucleatum, through the bacterial surface adhesin Fap2, have been shown to produce interleukin 8 (IL-8) and C-X-C Motif Chemokine Ligand 1 (CXCL1), which stimulate the spread of malignant cells [107]. This evidence concerns the gene CXCL8 and colonic neoplasm.