For instance, Meyer et al. [154] did not find sufficient evidence (with a relatively small cohort) that leptin levels in cord blood might be a predictor of fat distribution or obesity in early childhood (from 3 to 5 years), while Simpson et al. [165] have reported that cord blood leptin can weakly be associated to increased fat mass in late childhood (9 years). The gene discussed is LEP; the disease is obesity due to melanocortin 4 receptor deficiency.