BRCA1 and breast cancer: A 2008 study identified a deleterious BRCA1 or BRCA2 mutation in 2.6% (1 in 40) of unselected Cuban women with BC (n = 307) and reported four common mutations: BRCA1 185delAG, 5382insC, and the BRCA2 6174delT mutations common to Ashkenazi Jews and others of eastern European ancestry [21].