In a systematic review and meta-analysis done by Abdel-Maboud et al., Vitamin E supplementation significantly improved alanine transaminase (ALT), aspartate transaminase (AST), fibrosis, and NAFLD activity score (NAS) at early and late follow-up in adult patients and biochemical parameters in the long term follow up in pediatrics [1]. This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.