CD4 and tuberculosis: Based on the WHO guidance, each person diagnosed with HIV should have a CD4 test performed.1 Of those with a CD4 count of < 200 cells/μL, cryptococcal antigen (CrAg) and TB testing should be offered using a CrAg lateral flow assay (LFA) and Xpert/TB lipoarabinomannan (LAM) assay.1 Those with evidence of disease (i.e. positive tests) should be started on appropriate treatment; for example, TB preventive therapy should be started for those with latent TB infection.