To ascertain whether PRMT5 knockdown promoted an antitumor immunity, we performed flow cytometry analyses on these cell populations and found that the percentage of CD3+ T cells was significantly increased and the percentage of macrophages was notably decreased in the PRMT5 knockdown tumor microenvironment, while the percentages of other cells (such as DCs, B cells and NK cells) showed no statistical differences (Figure S2A). This evidence concerns the gene PRMT5 and neoplasm.