Analogously, the presence of phosphatidylserine, sialic acid, or heparin sulphate also contributed to the difference in the negative charge density of the cancer cell membrane as compared to their healthy counterparts 12, which facilitated the accumulation of the cationic AMPs selectively on the membrane surface of the cancer cells electrostatically and mediated membrane disruption via hydrophobic interaction with the lipophilic cell membrane 13, 14. Here, ADSL is linked to cancer.