As shown in the study by Yokoyama et al., SCGB3A2 and LPS administration induced pyroptosis and inhibited tumor growth by approximately 20% in the NSCLC cell lines NCI-H596, H358, H322, A549, and H157 and the CRC cell lines HCT116 and SW620. The gene discussed is SCGB3A2; the disease is neoplasm.