Using different human CRC cell lines and multiple patient-derived primary CRC cells isolated from primary tumors (Figure S1A and Table S2), we confirmed the most significant increase in PTPRC expression in both 5-fluorouracil (5-FU)-treated and irradiated CRC cells, with consistent results obtained for all tested cells (Figures 1B-C). The gene discussed is PTPRC; the disease is colorectal carcinoma.