The risk factors for disease-free survival were as follows (Table 3): tumor size ≥ 5 cm (HR: 2.754, 95% CI: 1.564-3.564, P = 0.012); microvascular invasion (HR: 2.012, 95% CI: 1.398-2.874, P = 0.002); and high PRMT4 expression (HR: 2.124, 95% CI: 1.654-3.812, P = 0.006). This evidence concerns the gene CARM1 and neoplasm.