In addition, some identified hub genes of the EC (TAGLN, GATA6, CDH3, CLU, COL8A1, MYH11, MYOCD) and EU (CXCL13, DDK-1, KLF4, CYP2E1, CYP4B1 and PROK1) have been reported be associated with endometriosis. This evidence concerns the gene PROK1 and endometriosis.