The most enriched GO functions according to the size of the different FDR values were shown in Figure 3B, and those in KEGG were AGE-RAGE signaling pathway in diabetic complications, fluid shear stress and atherosclerosis, staphylococcus aureus infection, amoebiasis, and bladder cancer (Figure 3C and 3D). The gene discussed is RENBP; the disease is amebiasis.