The notable HLA spatial cis-acting eQTLs involved SNPs rs2251396-PSORS1C1, rs2251396-MICA, rs3129889-HLA-DRB5 and rs9268645-HLA-DQB2 and were observed as contributing to the risk of developing T1D in multiple tissues (e.g. adrenal gland, transverse colon, small intestine, spleen, left heart ventricle, sun-exposed skin, testis and thyroid). The gene discussed is HLA-DQB2; the disease is type 1 diabetes mellitus.