Indeed, using an M30 antibody ELISA kit, alterations in levels of CK18 have been reported in breast cancer3, colorectal cancer4, ischemic stroke5, traumatic brain injury6, GVHD7 and particularly in various liver diseases including NASH and acute-on-chronic liver failure (ACLF)8. Here, KRT18 is linked to metabolic dysfunction-associated steatohepatitis.