The PPI network shows the targets involved in lung cancer and immunity were HSP90AA1, JUN, STAT3 EGFR, MYC, VEGFA, CCND1, TNF, MAPK1, AKT1, RELA, CDKN1A, TP53, IL2 and IL1B which were the major targets in lung cancer. This evidence concerns the gene CCND1 and lung cancer.