In addition, there were two genes (AKT interacting protein (Aktip) and nuclear receptor subfamily 1, group D, member 2 (Nrld2) which had changed levels of expression in the cortex of Chrm1−/− mice and BA 10 from people with schizophrenia that have also been shown to be associated with varying cognitive ability in humans. The gene discussed is CHRM1; the disease is schizophrenia.