XBP1 and colorectal carcinoma: We found that KCNQ1OT1 or XIST act as the sponge of miRNAs (miR-500a-3p, miR-370-3p, miR-2467-3p, miR-512-3p), accounting for the regulatory role of XBP-1-mediated ERS response in CRC tumorigenesis and development.