EZH2 and colorectal carcinoma: For example, a study by Zhuang et al. determined that lncRNA MALAT1 upregulated the SLAIN2 by sponging miR-106b-5p, thus enhancing the microtubules mobility and promoting the invasion and metastasis of CRC [33]; Xu et al. found that lncRNA SNHG6 was upregulated in CRC tissues and cells, and high expression of SNHG6 promoted CRC cell growth and metastasis by acting as a molecular sponge of miR-26a/b to regulate their common target EZH2 [34].