This cell line represents a model of spinocerebellar ataxia type 2 (25) useful for our testing because α-synuclein monomers, dimers, and trimers can readily be detected by Western blot (at estimated 17, 34 and 51 kDa, respectively) and its levels are highly increased. The gene discussed is SNCA; the disease is spinocerebellar ataxia type 2.