Consistent with COVID-19 CRS, we detected pSTAT3 in both mononuclear phagocytes (hereafter identified as either CD68+, F4/80+ or Ly6C+ cells) and neutrophils (hereafter identified as either NE+ cells or Ly6G+ cells) localized in vFLIP lung tissues compared to normal mice (Fig. 2C, Supplementary information, Fig. S3C). This evidence concerns the gene CD68 and COVID-19.