CD79A and malaria: However, for the original aseptic mosquito bite CHMI study, although a trend was present for dose response when comparing number of bites to parasite density at time of malaria diagnosis28, in the current study we did not observe a dose response when comparing number of bites to IgA or IgG responses, suggesting that the sporozoite dose may not explain the increased antibody responses in CHMI compared to natural infection.