Besides, elevations in the expression levels of KAT7, MnSOD, and catalase were observed in the left ventricular tissues of rats in the MI + AAV-sh-miR-134-5p groups (Fig. 6D, E), indicating that the therapeutic effect of miR-134-5p in preventing the adverse myocardial remodeling after MI was associated with KAT7-mediated ROS degradation. This evidence concerns the gene KAT7 and myocardial infarction.