The manuscript titled “Isoform-specific reduction of the bHLH transcription factor TCF4 levels in Huntington's disease” identified TCF4 as a transcription factor that is reduced in an isoform-specific manner in cell lines, animal models, and drug-induced models of Huntington’s as well as in postmortem hippocampal samples of human Huntington’s patients. This evidence concerns the gene TCF4 and juvenile Huntington disease.