Before 2014, testing was limited to a panel of six genes for LQTS (KCNQ1, KCNH2, SCN5A, KCNE1, KCNE2, KCNJ2), and sequencing of exon hotspots for CPVT (exons 1, 8, 14, 15, 44, 46, 47, 49, 88, 93, 95, 97, 101, 102, 103, 104, 105). The gene discussed is KCNE2; the disease is familial long QT syndrome.