IFNG and tuberculosis: Despite strategies implemented by the National TB Control Program, TB rates have changed little in recent years.3 Among the most recent recommendations of the Brazilian Ministry of Health was TPT for all TB contacts with a positive interferon-gamma release assay (IGRA) or tuberculin skin testing (TST), as well as all close contacts who are children≤5 years old or people living with HIV (PLWH), regardless of the test result.4