DMD and Duchenne muscular dystrophy: Of note, we showed that feeding with 1 mM putrescine mutants for dystrophin (Dysdet-1), a fly model of Duchenne muscle dystrophy (DMD), did not recover the Dys-dependent larval locomotor abnormalities (Figure 7D), indicating that the recovery of polyamine metabolism is specifically required for alleviating dCNBP loss-of-function locomotor defects.