SLC2A1 and esophageal squamous cell carcinoma: In this study, we investigated SLC2A1-AS1 expression in ESCA tissues by TCGA database and GEO dataset, the data from TCGA database revealed that SLC2A1-AS1 expression in 162 cases of ESCA samples was markedly higher than that in 11 cases of normal samples (Fig. 1A), with no difference between EAC samples and normal samples (P > 0.05) (Fig. 1B), but significance difference exhibited in ESCC samples and normal samples (P < 0.0001) (Fig. 1C), suggesting SLC2A1-AS1 may be a novel biomarker for discriminating EAC and ESCC histological types.