Conversely, miR-378a-3p inhibitor promoted cell proliferation and invasion and decreased apoptotic cell numbers (Supplementary Fig. 9A-E), whereas SLC2A1-AS1 and Glut1 silencing reversed in part the effects in ESCC cells (Supplementary Fig. 9A-E). The gene discussed is SLC2A1; the disease is esophageal squamous cell carcinoma.