EGFR and neoplasm: Without prior insight into the drug sensitivity of the DFCI202 model, we observed that the PDX tumor exhibited a low total EGFR transcript expression as determined by qPCR (Fig. 4B) and a significantly (P < 0.0001) lower EGFR L858R:MET signal ratio compared to the EGFR-dependent DFCI282 PDX model evaluated by BaseScope (Fig. 5E and fig.