However, there was no significant difference in terms of age, BMI, fat percentage, obesity degree percentage, waist circumference, waist-hip ratio, visceral fat, BFM, FMI, FBS, total cholesterol (TC), TG, HDL-C, high-sensitivity C-reactive Protein (hs-CRP), Galectin-3, TGF-β, and PAI-1 (P>0.05) (Table 2). The gene discussed is TGFB1; the disease is obesity due to melanocortin 4 receptor deficiency.