Furthermore, based on the protein level score, we performed ROC analysis, and the results demonstrated that ERMN (AUC = 0.86), MOBP (AUC = 0.846), PLP1 (AUC = 0.88), and OPALIN (AUC = 0.89) all showed high diagnostic value for distinguishing GBM tissues provided from older patients with high and low KPS (Figure 8b). Here, PLP1 is linked to glioblastoma.