To further analyze the relationship between the four genes (ERMN, MOBP, PLP1, and OPALIN) and KPS in older adults with GBM, 28 GBM tissues were provided by older adults with GBM with KPS ≥ 60 and 15 GBM tissues provided by older adults with GBM with KPS < 60 were set as the verification cohort. This evidence concerns the gene PLP1 and glioblastoma.