AKT1 and renal cell carcinoma: Collectively considering the evidence that the AKT pathway plays a critical role in malignant tumors with the results of the present study, we can hypothesize that hsa_circ_0002024 sponges hsa_miR_129-5p to regulate ASF1B and increase the occurrence, metastasis and fatality rate of RCC via the AKT pathway.