Reportedly, PCED1B-AS1 is elevated in gliomas and head and neck squamous cell carcinoma [13,27], and PCED1B-AS1 modulates the multiplication and apoptosis of gliomas via serving as ceRNA and regulating the miR-194-5p/PC-esterase domain containing 1B (PCED1B) axis [28]. Here, PCED1B is linked to head and neck squamous cell carcinoma.