Interestingly, many of these DEGs (such as IGFBP3 [31], ITGB3 [32], ZEB1 [33], GJA1 [34], MMP14 [35], GLI2 [36] and NCOA1 [37]) were previously reported to contribute to PCa progression. This evidence concerns the gene ITGB3 and posterior cortical atrophy.