Relative to the 6 normal thymuses and 2 thymomas, the 11 thymic NETs had significantly higher mRNA for neuroendocrine markers (more than 100-fold, P  < 0.02) chromogranin A, chromogranin B, neuron-specific enolase, and synaptophysin, confirming the neuroendocrine origin (Fig. 2E). This evidence concerns the gene CHGB and thymoma.