Several studies have identified mTOR as a key regulator of cardiac hypertrophy; for instance, the mTOR inhibitor rapamycin prevented heart-weight gain in an overload model of hypertrophy [5] and blocked cardiomyocyte size increase induced by Ang II [6] and phenylephrine [7] likely by inhibiting protein synthesis [7]. This evidence concerns the gene MTOR and cardiac hypertrophy.