Quantification of cardiomyocyte size and expression of hypertrophic genes using immunofluorescence staining of α-actin and western blot, respectively, demonstrated that UBQLN1 knockdown reversed the protective effect of miR-337-5p silencing on cardiac hypertrophy in vitro (Figure 5(c,d)). Here, UBQLN1 is linked to cardiac hypertrophy.