We also have analyzed 60 breast cancer samples by immunohistochemistry (IHC) and found FGFR2 is negatively correlated with YY1 and BRCA1 (Figure S4I, Supporting Information), suggesting that YY1 could be responsible for BRCA1 reduction in response to FGFR2 activation. This evidence concerns the gene FGFR2 and breast cancer.