Interestingly, a few years ago our group showed that a network of miRNAs significantly deregulated in CRC metastases (one of them being miR‐210, which is inducible by hypoxia; see above) downregulated Siah‐1 as well; thus, this particular action of E6 and E7 would add to a similar molecular axis of CRC progression and metastasis [174]. Here, SIAH1 is linked to colorectal carcinoma.