The similarity in recruitment of macrophages in uninjured skins (25) and hearts injected with α-gal nanoparticles (Figure 2B), strongly suggests that complement cleavage chemotactic peptides produced as a result of anti-Gal/α-gal nanoparticles interaction, shown to mediate recruitment of macrophages in the skin (25) have a similar chemotactic effect in post-MI reperfused hearts injected with these nanoparticles, as illustrated in Stage 1 of Figure 1. This evidence concerns the gene GAL and myocardial infarction.