In accordance with our sequencing data, miRNA-125a-5p, miRNA-128-3p, miRNA-221-3p, miRNA-222-3p, miRNA-223-5p, Msln, and Hmga2 significantly increased while miRNA-210-5p, miRNA-212-3p, Ces2e, Lgi2, Vsnl1, and Hpgds were found to be downregulated in the regenerative T1DM corneal epithelium. Here, MSLN is linked to type 1 diabetes mellitus.