Also, the expression of β-catenin, cyclin-D1, Gli1, Gli2, and Zinc finger E-box-binding homeobox 1 (ZEB1) was reduced, and conversely, the expression of E-cadherin, a downstream target of miR-200c, was improved in tumor tissues of murine treated with hUCMSC-IL-21 plus miR-200c (79). Here, IL21 is linked to neoplasm.